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Treating menopausal symptoms

Hormone replacement therapy (HRT) for women is the core of medical treatment for menopausal symptoms such as hot flushes, night sweats (vasomotor symptoms), and vaginal symptoms. It is used by millions of women worldwide to relieve the symptoms of menopause and usually does so very effectively as it partly compensates for the declining hormone levels around and after the menopause.

Ideally HRT should be used alongside a healthy lifestyle such as non-smoking, drinking alcohol in moderation, exercising regularly, eating a healthy diet and getting sufficient sunlight to maintain healthy levels of vitamin D in order to prevent osteoporosis.



Sources of hormones in HRT

Oestrogens and progestogens are the hormones most commonly employed in HRT. Many forms of HRT contain the oestrogen, 17-ß estradiol, which is identical to the natural female hormone. It is usually produced from plant material. Other oestrogens, known as conjugated equine estrogens are extracted from the urine of pregnant mares.

Natural progesterone is very poorly absorbed when taken as a tablet and therefore a number of synthetic alternatives (progestogens) have been developed. Progestogens in general act to protect the lining of the womb from over-stimulation by the hormone oestrogen.



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