Ultra low dose
Foot Notes
- Cauley JA, Robbins J, Chen Z et al. Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women’s Health Initiative randomised trial. J Am Med Assoc 2003; 290:1729-38.
- Lindsay R et al The minimum effective dose of estrogen for prevention of postmenopausal bone loss. Obstet Gynecol. 1984 Jun;63(6):759-63.
- Panay et al. Ultra-low-dose estradiol and norethisterone acetate: effective menopausal symptom relief Climacteric; 2007 Apr;10(2):120-31.
What is low / ultra low dose HRT? 2,3
Low and ultra low dose HRT means using the minimum effective dose of the hormones oestrogen and progestogen necessary to maintain the benefits of HRT.
| Treatment | Low dose HRT | Ultra low dose HRT* | Percentage reduction |
Oestrogen
(17ß-estradiol) | 1.0mg | 0.5mg | 50% less |
Progestogen
(NETA) | 0.5mg | 0.1mg | 80% less |
* available in the US and Canada.
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